Senior Technical Manager, Biorepository

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Overview

Has the responsibility and accountability for all technical and supports all administrative and personnel matters required for the efficient and high-quality operation and management of the Biorepository. Has the responsibility for development, interpretation and application of section policies and procedures, and long-range planning in conjunction with the Biorepository Directors. Is responsible for working with Biorepository leadership to ascertain client needs, develop specimen processing protocols, and evaluating services to ensure the Biorepository is providing state of the art sample processing, storage, and distribution services. Is responsible for training of personnel, documentation of staff competency, and execution of biorepository services.

Manages and directs the daily operations of the Biorepository, including approving work schedules, maintaining proper staffing, and supervising the daily work activities of research associates in the Biorepository. Responsible for producing laboratory procedures and policies and reviewing these documents as required by regulatory agencies or as needed for supporting laboratory operations. Documents and reviews the Biorepository’s technical performance in support of research studies and other service requests. Ensures appropriateness of specimen retrieval requests in coordination with Biorepository leadership. Works with Biorepository technical staff to ensure specimen requests are fulfilled promptly and according to standard operating procedures. Reviews study requests and support activities with biorepository leadership to determine feasibility, timeframe, and cost estimates. Interfaces with data scientists assigned to the Biorepository to ensure appropriate sample and data selection algorithms are used to support research sample requests. Ensures the Biorepository’s practices and procedures are compliant with regulatory guidelines and meet the standards of the College of American Pathologists (CAP). Adheres to all Hazcom, Universal Precautions, fire and safety policies and procedures. Responsible for annual staff retaining for all safety policies. Assists in preparation of developing QA standards and indicators as appropriate for the Biorepository. Ensures adequate laboratory supplies and sound inventory control within budget parameters. Ensures that all Biorepository laboratory equipment is properly maintained to include service contractual arrangements and facilitates repair when necessary. Responsible for ensuring temperature monitoring is ongoing and reviewed promptly. Takes corrective action when needed due to unacceptable temperature deviations of laboratory equipment. Participates in the selection and motivation of all laboratory personnel. Responsible for review and update of job descriptions as needed. Responsible for monitoring technical competency of technical personnel to include annual competency evaluation as per CAP regulations. Assists Biorepository leadership in development of capital and operating budget plans. Coordinates billing activities of the Biorepository with leadership team. Maintains membership in necessary professional societies and attends professional meetings as appropriate. Responsible for participating in the development and evaluation of new methodologies and technologies for use in the Biorepository.

Required Skills and Abilities

1. Proven success managing complex laboratory and biorepository operations, including Clinical Chemistry, Microbiology, Molecular Diagnostics, and Biobanking. Advanced proficiency in high-complexity laboratory techniques such as nucleic acid extraction, cell separation methods, sample processing, cell culture/sterile technique, and serological methods, sample workflow optimization, and operational efficiency.

2. Demonstrated ability to recruit, train, supervise, and evaluate technical and administrative staff. Skilled in performance management, employee development, coaching, and disciplinary processes while fostering a collaborative and productive work environment.

3. Comprehensive knowledge of laboratory regulatory requirements, quality assurance/quality improvement programs, and process improvement methodologies. Proven ability to ensure compliance, maintain operational excellence, and implement efficient workflows.

4. Strong project management and organizational skills with the ability to balance competing priorities, manage laboratory growth initiatives, and collaborate effectively with clinicians, researchers, vendors, and institutional partners. Demonstrated strategic thinking and independent decision-making.

5. Proven experience managing laboratory budgets, overseeing fiscal operations, and ensuring financial accountability. Proficient in laboratory information systems and databases, including Epic/Beaker, as well as Microsoft Office applications to support reporting, analysis, and operational management.

Preferred Skills and Abilities

1. Master’s Degree in a scientific discipline and eight years of experience or an equivalent combination of education and experience.

2. Advanced technical, managerial, computer, analytical, organizational and training skills.

3. Proven experience managing biorepositories. MT (ASCP) or similar certification.

Principal Responsibilities

1. Directs one or more functional areas within an administrative department of the University and ensure compliance with University policies and procedures. 2. Directs analytic and research support for educational policies and planning and develops and approves administrative policies affecting assigned functional areas of the University. 3. Directs and establishes parameters for major projects for the department and University. 4. Interprets federal policies and regulations and educates staff and administration about regulations, restrictions, and the legal responsibilities of the University. 5. Directs and implements policy and program modifications and develops standards to ensure compliance with federal, state and local regulations. 6. Develops and administers an operating budget for the assigned department consistent with University policies and procedures. 7. Develops cost savings objectives and goals; authorizes major purchases and negotiates contracts that range from routine to complex in nature. 8. Establishes and implements long- and short-range goals for the functional area consistent with University goals and objectives. 9. Directs the development of related automated systems to support the function; determines office policies and procedures for use of automated systems. 10. Directs the evaluation and selection of vendors and negotiates contract details including work steps and pricing with the vendors on behalf of the assigned functional area. 11. Works with internal and external contacts to solve problems that range from routine to complex in nature. 12. Represents the University in discussions and negotiations with various governmental agencies. 13. Directs a staff of exempt and nonexempt employees. 14. May perform other duties as assigned. Required Education and Experience Bachelor’s Degree in related field. Six years of experience or an equivalent combination of education and experience.

Job Posting Date

07/16/2026

Job Category

Manager

Bargaining Unit

NON

Compensation Grade

Administration & Operations

Compensation Grade Profile

Leader (27)

Salary Range

$105,000.00 - $174,000.00

Time Type

Full time

Duration Type

Staff

Work Model

On-site

Background Check Requirements

All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.

Health Requirements

Certain positions have associated health requirements based on specific job responsibilities. These may include vaccinations, tests, or examinations, as required by law, regulation, or university policy.

Posting Disclaimer

Salary offers are determined by a candidate’s qualifications, experience, skills, and education in relation to the position requirements, along with the role’s grade profile and current internal and external market conditions.

The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the position. Employees will be assigned specific job-related duties through  their hiring department.

The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual’s sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.

Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).

Note

Yale University is a tobacco-free campus.